8ZQQ

Human high-affinity choline transporter CHT1 bound to choline under NaCl condition, with sodium and chloride ions coordinated.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001701	biological_process	in utero embryonic development
A	0005307	molecular_function	choline:sodium symporter activity
A	0005768	cellular_component	endosome
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0006814	biological_process	sodium ion transport
A	0006836	biological_process	neurotransmitter transport
A	0007271	biological_process	synaptic transmission, cholinergic
A	0007274	biological_process	neuromuscular synaptic transmission
A	0008292	biological_process	acetylcholine biosynthetic process
A	0015220	molecular_function	choline transmembrane transporter activity
A	0015293	molecular_function	symporter activity
A	0015871	biological_process	choline transport
A	0016020	cellular_component	membrane
A	0022857	molecular_function	transmembrane transporter activity
A	0030424	cellular_component	axon
A	0030425	cellular_component	dendrite
A	0030672	cellular_component	synaptic vesicle membrane
A	0031410	cellular_component	cytoplasmic vesicle
A	0031594	cellular_component	neuromuscular junction
A	0031901	cellular_component	early endosome membrane
A	0033265	molecular_function	choline binding
A	0042734	cellular_component	presynaptic membrane
A	0042995	cellular_component	cell projection
A	0043025	cellular_component	neuronal cell body
A	0043204	cellular_component	perikaryon
A	0045202	cellular_component	synapse
A	0055085	biological_process	transmembrane transport
A	0098793	cellular_component	presynapse

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	240
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	105
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	86
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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