8ZC5
SARS-CoV-2 Omicron BA.4 spike trimer (6P) in complex with D1F6 Fab, focused refinement of RBD region
Summary for 8ZC5
Entry DOI | 10.2210/pdb8zc5/pdb |
EMDB information | 39923 |
Descriptor | Spike protein S1, Light chain of D1F6 Fab, Heavy chain of D1F6 Fab, ... (4 entities in total) |
Functional Keywords | spike protein, antibody fab fragment, complex, viral protein/immune system, viral protein-immune system complex |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More |
Total number of polymer chains | 6 |
Total formula weight | 96297.58 |
Authors | |
Primary citation | Liu, B.,Niu, X.,Deng, Y.,Zhang, Z.,Wang, Y.,Gao, X.,Liang, H.,Li, Z.,Wang, Q.,Cheng, Y.,Chen, Q.,Huang, S.,Pan, Y.,Su, M.,Lin, X.,Niu, C.,Chen, Y.,Yang, W.,Zhang, Y.,Yan, Q.,He, J.,Zhao, J.,Chen, L.,Xiong, X. An unconventional VH1-2 antibody tolerates escape mutations and shows an antigenic hotspot on SARS-CoV-2 spike. Cell Rep, 43:114265-114265, 2024 Cited by PubMed: 38805396DOI: 10.1016/j.celrep.2024.114265 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.91 Å) |
Structure validation
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