8XNK

Cryo-EM structure of SARS-CoV-2 Omicron HV.1 spike protein(6P) in complex with human ACE2

Summary for 8XNK

• Entry DOI: 10.2210/pdb8xnk/pdb
• EMDB information: 38505
• Descriptor: Angiotensin-converting enzyme 2, Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: sars-cov-2, omicron, hv.1, spike protein, human ace2, viral protein, hydrolase-viral protein complex, hydrolase/viral protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 485684.52

Authors

Li, L.J.,Gu, Y.H.,Shi, K.Y.,Qi, J.X.,Gao, G.F. (deposition date: 2023-12-30, release date: 2024-07-03, Last modification date: 2024-08-21)

• Primary citation: Li, L.,Shi, K.,Gu, Y.,Xu, Z.,Shu, C.,Li, D.,Sun, J.,Cong, M.,Li, X.,Zhao, X.,Yu, G.,Hu, S.,Tan, H.,Qi, J.,Ma, X.,Liu, K.,Gao, G.F.; Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.; Structure, 32:1055-1067.e6, 2024; PubMed: 39013463; DOI: 10.1016/j.str.2024.06.012

Experimental method

ELECTRON MICROSCOPY (2.78 Å)