8WUY
Crystal Structure of TR3 LBD in complex with para-positioned 3,4,5-trisubstituted benzene derivatives
Summary for 8WUY
Entry DOI | 10.2210/pdb8wuy/pdb |
Descriptor | Nuclear receptor subfamily 4immunitygroup A member 1, ~{N}-methyl-~{N}-octyl-3,4,5-tris(oxidanyl)benzamide (3 entities in total) |
Functional Keywords | complex, transcription |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 55381.30 |
Authors | Hong, W.B.,Chen, X.Q.,Lin, T.W. (deposition date: 2023-10-21, release date: 2024-01-24, Last modification date: 2024-01-31) |
Primary citation | Hong, W.,Xiao, T.,Lin, G.,Liu, C.,Li, H.,Li, Y.,Hu, H.,Wu, S.,Wang, S.,Liang, Z.,Lin, T.,Liu, J.,Chen, X. Structure-based design and synthesis of anti-fibrotic compounds derived from para-positioned 3,4,5-trisubstituted benzene. Bioorg.Chem., 144:107113-107113, 2024 Cited by PubMed: 38232685DOI: 10.1016/j.bioorg.2024.107113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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