8WLR

Cryo-EM structure of SARS-CoV-2 prototype spike protein receptor-binding domain in complex with hippopotamus ACE2

Summary for 8WLR

• Entry DOI: 10.2210/pdb8wlr/pdb
• EMDB information: 37629
• Descriptor: Angiotensin-converting enzyme, Spike glycoprotein, ZINC ION, ... (4 entities in total)
• Functional Keywords: complex, viral protein/hydrolase, viral protein-hydrolase complex
• Biological source: Hippopotamus amphibius; More
• Total number of polymer chains: 2
• Total formula weight: 204741.37

Authors

Han, P.,Yang, R.R.,Li, S.H. (deposition date: 2023-09-30, release date: 2024-03-27, Last modification date: 2024-06-05)

• Primary citation: Yang, R.,Han, P.,Han, P.,Li, D.,Zhao, R.,Niu, S.,Liu, K.,Li, S.,Tian, W.X.,Gao, G.F.; Molecular basis of hippopotamus ACE2 binding to SARS-CoV-2.; J.Virol., 98:e0045124-e0045124, 2024; PubMed: 38591877; DOI: 10.1128/jvi.00451-24

Experimental method

ELECTRON MICROSCOPY (3.12 Å)