8WBZ
Cryo-EM structure of ACE2-B0AT1 complex with JX225
Summary for 8WBZ
Entry DOI | 10.2210/pdb8wbz/pdb |
EMDB information | 37428 |
Descriptor | Sodium-dependent neutral amino acid transporter B(0)AT1, Angiotensin-converting enzyme 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | transporter, complex, inhibitors, protein transport, protein transport-hydrolase complex, protein transport/hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 342910.68 |
Authors | |
Primary citation | Xu, J.,Hu, Z.,Dai, L.,Yadav, A.,Jiang, Y.,Broer, A.,Gardiner, M.G.,McLeod, M.,Yan, R.,Broer, S. Molecular basis of inhibition of the amino acid transporter B 0 AT1 (SLC6A19). Nat Commun, 15:7224-7224, 2024 Cited by PubMed: 39174516DOI: 10.1038/s41467-024-51748-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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