8W9W
The cryo-EM structure of human sphingomyelin synthase-related protein in complex with ceramide/phosphoethanolamine
Summary for 8W9W
Entry DOI | 10.2210/pdb8w9w/pdb |
EMDB information | 37383 |
Descriptor | Sphingomyelin synthase-related protein 1, ~{N}-[(~{Z},2~{S},3~{R})-1,3-bis(oxidanyl)heptadec-4-en-2-yl]dodecanamide, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER (3 entities in total) |
Functional Keywords | synthase, sphingomyelin, cpe, membrane protein, lipid metabolism |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 6 |
Total formula weight | 189710.03 |
Authors | |
Primary citation | Hu, K.,Zhang, Q.,Chen, Y.,Yang, J.,Xia, Y.,Rao, B.,Li, S.,Shen, Y.,Cao, M.,Lu, H.,Qin, A.,Jiang, X.C.,Yao, D.,Zhao, J.,Zhou, L.,Cao, Y. Cryo-EM structure of human sphingomyelin synthase and its mechanistic implications for sphingomyelin synthesis. Nat.Struct.Mol.Biol., 31:884-895, 2024 Cited by PubMed: 38388831DOI: 10.1038/s41594-024-01237-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.74 Å) |
Structure validation
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