8VZX

Q108K:K40L:T53A:R58F mutant of hCRBPII bound to synthetic fluorophore TD-1V

This is a non-PDB format compatible entry.

Summary for 8VZX

• Entry DOI: 10.2210/pdb8vzx/pdb
• Descriptor: Retinol-binding protein 2, ACETATE ION, (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal, ... (4 entities in total)
• Functional Keywords: human cellular retinol binding protein ii, hcrbpii, td-1v, engineered protein, fluorescent protein, retinol binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 62948.67

Authors

Nossoni, Z.,Bingham, C.R.,Geiger, J.H. (deposition date: 2024-02-13, release date: 2024-04-03, Last modification date: 2024-09-04)

• Primary citation: Santos, E.M.,Chandra, I.,Assar, Z.,Sheng, W.,Ghanbarpour, A.,Bingham, C.,Vasileiou, C.,Geiger, J.H.,Borhan, B.; Regulation of Absorption and Emission in a Protein/Fluorophore Complex.; Acs Chem.Biol., 19:1725-1732, 2024; PubMed: 39046136; DOI: 10.1021/acschembio.4c00125

Experimental method

X-RAY DIFFRACTION (1.47 Å)