8VY9
CryoEM structure of Ggust-coupled TAS2R14 with cholesterol and an intracellular tastant
This is a non-PDB format compatible entry.
Summary for 8VY9
Entry DOI | 10.2210/pdb8vy9/pdb |
Related | 8VY7 |
EMDB information | 43647 43650 43656 |
Descriptor | Guanine nucleotide-binding protein G(t) subunit alpha-3, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total) |
Functional Keywords | gpcr, complex, signaling protein, taste receptor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 193366.32 |
Authors | Kim, Y.,Gumpper, R.H.,Roth, B.L. (deposition date: 2024-02-07, release date: 2024-04-03, Last modification date: 2024-04-24) |
Primary citation | Kim, Y.,Gumpper, R.H.,Liu, Y.,Kocak, D.D.,Xiong, Y.,Cao, C.,Deng, Z.,Krumm, B.E.,Jain, M.K.,Zhang, S.,Jin, J.,Roth, B.L. Bitter taste receptor activation by cholesterol and an intracellular tastant. Nature, 628:664-671, 2024 Cited by PubMed: 38600377DOI: 10.1038/s41586-024-07253-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.88 Å) |
Structure validation
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