8VBY

Structure of the human dopamine transporter in complex with beta-CFT, MRS7292 and divalent zinc

This is a non-PDB format compatible entry.

Summary for 8VBY

• Entry DOI: 10.2210/pdb8vby/pdb
• EMDB information: 43128
• Descriptor: Sodium-dependent dopamine transporter, SODIUM ION, DODECANE, ... (14 entities in total)
• Functional Keywords: transport, membrane, inhibitor, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 70286.05

Authors

Srivastava, D.K.,Gouaux, E. (deposition date: 2023-12-12, release date: 2024-08-07, Last modification date: 2024-09-04)

• Primary citation: Srivastava, D.K.,Navratna, V.,Tosh, D.K.,Chinn, A.,Sk, M.F.,Tajkhorshid, E.,Jacobson, K.A.,Gouaux, E.; Structure of the human dopamine transporter and mechanisms of inhibition.; Nature, 632:672-677, 2024; PubMed: 39112705; DOI: 10.1038/s41586-024-07739-9

Experimental method

ELECTRON MICROSCOPY (3.19 Å)