8V6S
Crystal structure of PcThsA in complex with Imidazole Adenine Dinucleotide
Summary for 8V6S
Entry DOI | 10.2210/pdb8v6s/pdb |
Descriptor | Thoeris protein ThsA Macro domain-containing protein, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-imidazol-1-yl-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate (3 entities in total) |
Functional Keywords | antiphage immunity, nucleotide signalling, immune system |
Biological source | Pseudomonas corrugata |
Total number of polymer chains | 2 |
Total formula weight | 56395.72 |
Authors | Shi, Y.,Masic, V.,Mosaiab, T.,Goulart, C.C.,Hartley-Tassell, L.,Sorbello, M.,Vasquez, E.,Mishra, B.P.,Holt, S.,Gu, W.,Kobe, B.,Ve, T. (deposition date: 2023-12-02, release date: 2024-06-12, Last modification date: 2024-07-10) |
Primary citation | Shi, Y.,Masic, V.,Mosaiab, T.,Rajaratman, P.,Hartley-Tassell, L.,Sorbello, M.,Goulart, C.C.,Vasquez, E.,Mishra, B.P.,Holt, S.,Gu, W.,Kobe, B.,Ve, T. Structural characterization of macro domain-containing Thoeris antiphage defense systems. Sci Adv, 10:eadn3310-eadn3310, 2024 Cited by PubMed: 38924412DOI: 10.1126/sciadv.adn3310 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
Download full validation report