8UWP
Crystal structure of SETDB1 Tudor domain in complex with MR46747
Summary for 8UWP
Entry DOI | 10.2210/pdb8uwp/pdb |
Descriptor | Histone-lysine N-methyltransferase SETDB1, (3S)-N-(4-chloro-3-{[2-(diethylamino)ethyl]carbamoyl}phenyl)-3-(diethylamino)pyrrolidine-1-carboxamide, SULFATE ION, ... (6 entities in total) |
Functional Keywords | setdb1, epigenetics, methyllysine reader, sgc, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 54747.77 |
Authors | Shrestha, S.,Beldar, S.,Dong, A.,Ackloo, S.,Brown, P.J.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC) (deposition date: 2023-11-07, release date: 2023-11-22, Last modification date: 2024-01-17) |
Primary citation | Shrestha, S.,Beldar, S.,Dong, A.,Ackloo, S.,Brown, P.J.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC) Crystal structure of SETDB1 Tudor domain in complex with MR46747 To be published, |
Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
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