8TLX
Crystal structure of MBP and AF9 AHD fusion protein 3AQA in complex with peptidomimetic inhibitor 21a
Summary for 8TLX
Entry DOI | 10.2210/pdb8tlx/pdb |
Related PRD ID | PRD_900001 |
Descriptor | MBP and AF9 AHD fusion protein 3AQA, peptidomimetic inhibitor 21a, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | mll fusion super elongation complex (sec) acute lymphoblastic leukemia acute myeloid leukemia, translation |
Biological source | Escherichia coli K-12 More |
Total number of polymer chains | 2 |
Total formula weight | 50311.85 |
Authors | Yang, Y.,Nikolovska-Coleska, Z. (deposition date: 2023-07-27, release date: 2024-05-29, Last modification date: 2024-09-11) |
Primary citation | Yang, Y.,Ahmad, E.,Premkumar, V.,Liu, A.,Ashikur Rahman, S.M.,Nikolovska-Coleska, Z. Structural studies of intrinsically disordered MLL-fusion protein AF9 in complex with peptidomimetic inhibitors. Protein Sci., 33:e5019-e5019, 2024 Cited by PubMed: 38747396DOI: 10.1002/pro.5019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.097 Å) |
Structure validation
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