8TLX
Crystal structure of MBP and AF9 AHD fusion protein 3AQA in complex with peptidomimetic inhibitor 21a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | MBP and AF9 AHD fusion protein 3AQA | polymer | 442 | 48890.2 | 1 | UniProt (P0AEX9) UniProt (P42568) Pfam (PF01547) Pfam (PF17793) In PDB | Escherichia coli K-12 | |
| 2 | B | peptidomimetic inhibitor 21a | polymer | 9 | 803.0 | 1 | synthetic construct | ||
| 3 | C | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900001) GlyTouCan (G07411ON) | |||
| 4 | A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 354 | Chemie (HOH) |
Sequence modifications
A: 2 - 367 (UniProt: P0AEX9)
A: 500 - 568 (UniProt: P42568)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Cys 336 | Gln 361 | engineered mutation |
| Ala 368 | - | linker |
| Ala 369 | - | linker |
| Ala 370 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Cys 502 | Ala 502 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49693.3 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 276.3 | |
| All* | Total formula weight | 50311.8 |
