8T88
FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, Oxadiazolone JJ004 bound
Summary for 8T88
Entry DOI | 10.2210/pdb8t88/pdb |
Descriptor | Fluorophosphonate-binding serine hydrolase E, methyl 2-formyl-2-[4-(undec-10-ynamido)phenyl]hydrazine-1-carboxylate, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | fphe, staphylococcus aureus, s. aureus, fluorophosphonate-binding, serine hydrolases, lipase, hydrolase |
Biological source | Staphylococcus aureus USA300-0114 |
Total number of polymer chains | 2 |
Total formula weight | 63345.70 |
Authors | Fellner, M. (deposition date: 2023-06-22, release date: 2024-03-06, Last modification date: 2024-03-27) |
Primary citation | Jo, J.,Upadhyay, T.,Woods, E.C.,Park, K.W.,Pedowitz, N.J.,Jaworek-Korjakowska, J.,Wang, S.,Valdez, T.A.,Fellner, M.,Bogyo, M. Development of Oxadiazolone Activity-Based Probes Targeting FphE for Specific Detection of Staphylococcus aureus Infections. J.Am.Chem.Soc., 146:6880-6892, 2024 Cited by PubMed: 38411555DOI: 10.1021/jacs.3c13974 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.54 Å) |
Structure validation
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