8T7A

Cryo-EM structure of RSV preF in complex with Fab 2.4K

Summary for 8T7A

• Entry DOI: 10.2210/pdb8t7a/pdb
• EMDB information: 41089
• Descriptor: Fusion glycoprotein F2, Fusion glycoprotein F1, 2.4K Fab Heavy Chain, ... (5 entities in total)
• Functional Keywords: complex, antibody, fusion protein, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Respiratory syncytial virus; More
• Total number of polymer chains: 12
• Total formula weight: 252473.78

Authors

McCool, R.S.,McLellan, J.S. (deposition date: 2023-06-20, release date: 2023-09-13, Last modification date: 2023-11-08)

• Primary citation: McCool, R.S.,Musayev, M.,Bush, S.M.,Derrien-Colemyn, A.,Acreman, C.M.,Wrapp, D.,Ruckwardt, T.J.,Graham, B.S.,Mascola, J.R.,McLellan, J.S.; Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein elicits antibodies targeting a membrane-proximal epitope.; J.Virol., 97:e0092923-e0092923, 2023; PubMed: 37737588; DOI: 10.1128/jvi.00929-23

Experimental method

ELECTRON MICROSCOPY (2.8 Å)