8T6J
CDPPB-bound inactive mGlu5
Summary for 8T6J
Entry DOI | 10.2210/pdb8t6j/pdb |
EMDB information | 41069 41783 41787 |
Descriptor | Metabotropic glutamate receptor 5, 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide (2 entities in total) |
Functional Keywords | gpcr, signaling protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 198465.39 |
Authors | Krishna Kumar, K.,Wang, H.,Kobilka, B.K. (deposition date: 2023-06-16, release date: 2023-10-11, Last modification date: 2024-06-05) |
Primary citation | Krishna Kumar, K.,Wang, H.,Habrian, C.,Latorraca, N.R.,Xu, J.,O'Brien, E.S.,Zhang, C.,Montabana, E.,Koehl, A.,Marqusee, S.,Isacoff, E.Y.,Kobilka, B.K. Stepwise activation of a metabotropic glutamate receptor. Nature, 629:951-956, 2024 Cited by PubMed: 38632403DOI: 10.1038/s41586-024-07327-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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