8T5K
Crystal structure of STING CTD in complex with BDW-OH
Summary for 8T5K
Entry DOI | 10.2210/pdb8t5k/pdb |
Descriptor | Stimulator of interferon genes protein, {[(4S)-8,9-dimethylthieno[3,2-e][1,2,4]triazolo[4,3-c]pyrimidin-3-yl]sulfanyl}acetic acid (3 entities in total) |
Functional Keywords | mediator of irf3 activation, stimulator of interferon genes protein, antiviral protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 21851.58 |
Authors | |
Primary citation | Tang, Z.,Zhao, J.,Li, Y.,Tomer, S.,Selvaraju, M.,Tien, N.,Sun, D.,Johnson, D.K.,Zhen, A.,Li, P.,Wang, J. Structural and Biological Evaluations of a Non-Nucleoside STING Agonist Specific for Human STING A230 Variants. Biorxiv, 2023 Cited by PubMed: 37425806DOI: 10.1101/2023.07.02.547363 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
Download full validation report