8SU8
Co-crystal structure of KRIT1 with a 1-hydroxy 2-naphthaldehyde derivative (6-(furan-2-yl)-2-hydroxy-1-naphthaldehyde).
Summary for 8SU8
Entry DOI | 10.2210/pdb8su8/pdb |
Descriptor | Krev interaction trapped protein 1, Ras-related protein Rap-1b, (6P)-6-(furan-2-yl)-2-hydroxynaphthalene-1-carbaldehyde, ... (6 entities in total) |
Functional Keywords | complex, inhibitor, cell adhesion |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 56822.19 |
Authors | |
Primary citation | Francisco, K.R.,Bruystens, J.,Varricchio, C.,McCurdy, S.,Wu, J.,Lopez-Ramirez, M.A.,Ginsberg, M.,Caffrey, C.R.,Brancale, A.,Gingras, A.R.,Hixon, M.S.,Ballatore, C. Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein-Protein Interaction Inhibitors. Acs Pharmacol Transl Sci, 6:1651-1658, 2023 Cited by PubMed: 37974623DOI: 10.1021/acsptsci.3c00156 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.01 Å) |
Structure validation
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