8SU8
Co-crystal structure of KRIT1 with a 1-hydroxy 2-naphthaldehyde derivative (6-(furan-2-yl)-2-hydroxy-1-naphthaldehyde).
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Krev interaction trapped protein 1 | polymer | 318 | 37017.9 | 1 | UniProt (O00522) Pfam (PF00373) | Homo sapiens (Human) | Krev interaction trapped 1,Cerebral cavernous malformations 1 protein |
| 2 | B (B) | Ras-related protein Rap-1b | polymer | 167 | 19019.5 | 1 | UniProt (P61224) Pfam (PF00071) | Homo sapiens (Human) | GTP-binding protein smg p21B |
| 3 | C (A) | (6P)-6-(furan-2-yl)-2-hydroxynaphthalene-1-carbaldehyde | non-polymer | 238.2 | 1 | Chemie (XE2) | |||
| 4 | D (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E (B) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 74 | Chemie (HOH) |
Sequence modifications
B: 1 - 167 (UniProt: P61224)
| PDB | External Database | Details |
|---|---|---|
| Gln 62 | Glu 62 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56037.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 784.7 | |
| All* | Total formula weight | 56822.2 |
