8R1T
Pim1 in complex with 4-(4-aminophenethyl)benzoic acid and Pimtide
Summary for 8R1T
Entry DOI | 10.2210/pdb8r1t/pdb |
Related | 7QB2 7QFM 7Z6U 8AFR 8R0H 8R0Q 8R0W 8R0Y 8R10 8R18 8R1K 8R1N 8R1P |
Descriptor | Serine/threonine-protein kinase pim-1, Pimtide, GLYCEROL, ... (5 entities in total) |
Functional Keywords | serine kinase, kinase, complex, pim1, pim, pim-1, inhibitor, tumorigenisis, cancer, pimtide, proto oncogen, atp, phosphorylation, apoptosis, cell cycle, transferase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 37596.71 |
Authors | Hochban, P.M.M.,Heine, A.,Diederich, W.E. (deposition date: 2023-11-02, release date: 2024-03-20, Last modification date: 2024-06-12) |
Primary citation | Hochban, P.M.M.,Heyder, L.,Heine, A.,Diederich, W.E. What doesn't fit is made to fit: Pim-1 kinase adapts to the configuration of stilbene-based inhibitors. Arch Pharm, 357:e2400094-e2400094, 2024 Cited by PubMed: 38631036DOI: 10.1002/ardp.202400094 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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