8QHE
Crystal structure IR-09
Summary for 8QHE
Entry DOI | 10.2210/pdb8qhe/pdb |
Descriptor | 6-phosphogluconate dehydrogenase NADP-binding domain-containing protein, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ~{N}-methylcyclohexanamine, ... (5 entities in total) |
Functional Keywords | reductase, biosynthetic protein |
Biological source | Aspergillus lentulus |
Total number of polymer chains | 1 |
Total formula weight | 33068.60 |
Authors | Levy, C.W. (deposition date: 2023-09-07, release date: 2023-10-11, Last modification date: 2023-10-25) |
Primary citation | Casamajo, A.R.,Yu, Y.,Schnepel, C.,Morrill, C.,Barker, R.,Levy, C.W.,Finnigan, J.,Spelling, V.,Westerlund, K.,Petchey, M.,Sheppard, R.J.,Lewis, R.J.,Falcioni, F.,Hayes, M.A.,Turner, N.J. Biocatalysis in Drug Design: Engineered Reductive Aminases (RedAms) Are Used to Access Chiral Building Blocks with Multiple Stereocenters. J.Am.Chem.Soc., 145:22041-22046, 2023 Cited by PubMed: 37782882DOI: 10.1021/jacs.3c07010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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