8QEX

Streptavidin variant with a cobalt catalyst for CH metal-catalyzed hydrogen-atom-transfer (M-HAT)

Summary for 8QEX

Entry DOI	10.2210/pdb8qex/pdb
Descriptor	Streptavidin, cobalt Streptavidin (3 entities in total)
Functional Keywords	metal-catalyzed hydrogen-atom-transfer, artificial radical cyclase, protein design, metal binding protein
Biological source	Streptomyces avidinii More
Total number of polymer chains	2
Total formula weight	36487.62
Authors	Jakob, R.P.,Chen, D.,Ward, T.R. (deposition date: 2023-09-01, release date: 2024-07-31)
Primary citation	Chen, D.,Zhang, X.,Vorobieva, A.A.,Tachibana, R.,Stein, A.,Jakob, R.P.,Zou, Z.,Graf, D.A.,Li, A.,Maier, T.,Correia, B.E.,Ward, T.R. An evolved artificial radical cyclase enables the construction of bicyclic terpenoid scaffolds via an H-atom transfer pathway. Nat.Chem., 2024 Cited by PubMed: 39030420 DOI: 10.1038/s41557-024-01562-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation