8PXX
Structure of the WW domain tandem of PRPF40A in complex with SF1
Summary for 8PXX
Entry DOI | 10.2210/pdb8pxx/pdb |
NMR Information | BMRB: 34840 |
Descriptor | Pre-mRNA-processing factor 40 homolog A, Splicing factor 1 (2 entities in total) |
Functional Keywords | ww domain tandem, proline-rich peptide, alternative splicing regulation, e complex, splicing |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 13865.38 |
Authors | Martinez-Lumbreras, S.,Sattler, M. (deposition date: 2023-07-24, release date: 2024-04-03, Last modification date: 2024-05-22) |
Primary citation | Martinez-Lumbreras, S.,Trager, L.K.,Mulorz, M.M.,Payr, M.,Dikaya, V.,Hipp, C.,Konig, J.,Sattler, M. Intramolecular autoinhibition regulates the selectivity of PRPF40A tandem WW domains for proline-rich motifs. Nat Commun, 15:3888-3888, 2024 Cited by PubMed: 38719828DOI: 10.1038/s41467-024-48004-x PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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