8PXX

Structure of the WW domain tandem of PRPF40A in complex with SF1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Pre-mRNA-processing factor 40 homolog A	polymer	99	11450.7	1	UniProt (O75400) Pfam (PF00397) In PDB	Homo sapiens (human)	Fas ligand-associated factor 1,Formin-binding protein 11,Formin-binding protein 3,Huntingtin yeast partner A,Huntingtin-interacting protein 10,HIP-10,Huntingtin-interacting protein A,Renal carcinoma antigen NY-REN-6
2	B	Splicing factor 1	polymer	27	2414.7	1	UniProt (Q15637) In PDB	Homo sapiens (human)	Mammalian branch point-binding protein,BBP,mBBP,Transcription factor ZFM1,Zinc finger gene in MEN1 locus,Zinc finger protein 162

Sequence modifications

A: 141 - 236 (UniProt: O75400)

PDB	External Database	Details
Gly 138	-	expression tag
Ala 139	-	expression tag
Met 140	-	expression tag

B: 575 - 590 (UniProt: Q15637)

PDB	External Database	Details
Gly 569	-	expression tag
Ala 570	-	expression tag
Met 571	-	expression tag
Ser 572	-	expression tag
Gly 573	-	expression tag
Ser 574	-	expression tag
Ser 591	-	expression tag
Gly 592	-	expression tag
Ser 593	-	expression tag
Gly 594	-	expression tag
Asn 595	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	13865.4
All*	Total formula weight	13865.4

*Water molecules are not included.