8PWD
Crystal structure of VDR in complex Des-C-Ring and Aromatic-D-Ring analog 3c
Summary for 8PWD
Entry DOI | 10.2210/pdb8pwd/pdb |
Descriptor | Vitamin D3 receptor A, Nuclear receptor coactivator 2, (1R,3S,5Z)-4-methylidene-5-[(E)-3-[3-[7,7,7-tris(fluoranyl)-6-oxidanyl-6-(trifluoromethyl)hept-3-ynyl]phenyl]pent-2-enylidene]cyclohexane-1,3-diol, ... (4 entities in total) |
Functional Keywords | nuclear receptor, vdr, agonist, transcription |
Biological source | Danio rerio (zebrafish) More |
Total number of polymer chains | 2 |
Total formula weight | 36143.03 |
Authors | |
Primary citation | Rochel, N. Novel Des-C-Ring and Aromatic-D-Ring analogs Acting as Potent Agonists of the Vitamin D Receptor (VDR) To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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