8PVS
Targeting extended blood antigens by Akkermansia muciniphila enzymes unveils a missing link for generating universal donor blood
This is a non-PDB format compatible entry.
Summary for 8PVS
Entry DOI | 10.2210/pdb8pvs/pdb |
Descriptor | Alpha-1,3-galactosidase B, alpha-D-galactopyranose, 1,2-ETHANEDIOL, ... (7 entities in total) |
Functional Keywords | alpha-galactosidase, akkermansia muciniphila, blood conversion, beta-helix, hydrolase |
Biological source | Akkermansia muciniphila |
Total number of polymer chains | 2 |
Total formula weight | 162863.71 |
Authors | Jensen, M.,Abou Hachem, M.,Morth, J.P. (deposition date: 2023-07-18, release date: 2024-02-28, Last modification date: 2024-05-22) |
Primary citation | Jensen, M.,Stenfelt, L.,Ricci Hagman, J.,Pichler, M.J.,Weikum, J.,Nielsen, T.S.,Hult, A.,Morth, J.P.,Olsson, M.L.,Abou Hachem, M. Akkermansia muciniphila exoglycosidases target extended blood group antigens to generate ABO-universal blood. Nat Microbiol, 9:1176-1188, 2024 Cited by PubMed: 38684911DOI: 10.1038/s41564-024-01663-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.68 Å) |
Structure validation
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