8PS2
Asymmetric unit of the yeast fatty acid synthase with ACP at the enoyl reductase domain (FASam sample)
Summary for 8PS2
Entry DOI | 10.2210/pdb8ps2/pdb |
EMDB information | 17843 |
Descriptor | Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, ~{S}-[2-[3-[[(2~{R})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (~{E})-but-2-enethioate, ... (5 entities in total) |
Functional Keywords | fatty acid synthase, acyl carrier protein, fas, acp, cytosolic protein |
Biological source | Saccharomyces cerevisiae (baker's yeast) More |
Total number of polymer chains | 3 |
Total formula weight | 645045.57 |
Authors | |
Primary citation | Singh, K.,Bunzel, G.,Graf, B.,Yip, K.M.,Neumann-Schaal, M.,Stark, H.,Chari, A. Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots. Cell, 186:5054-5067.e16, 2023 Cited by PubMed: 37949058DOI: 10.1016/j.cell.2023.10.009 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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