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8PJK

ST171-bound serotonin 5-HT1A receptor - Gi Protein Complex

Summary for 8PJK
Entry DOI10.2210/pdb8pjk/pdb
EMDB information17712 17747
DescriptorGuanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (8 entities in total)
Functional Keywordsmembrane protein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains4
Total formula weight140615.92
Authors
Schneider, J.,Gmeiner, P.,Rasmussen, T.,Boettcher, B. (deposition date: 2023-06-23, release date: 2024-05-29, Last modification date: 2024-11-13)
Primary citationBoettcher, B.
Discovery of a functionally selective serotonin 1A receptor agonist for the treatment of pain
To Be Published,
Experimental method
ELECTRON MICROSCOPY (2.4 Å)
Structure validation

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PDB entries from 2024-11-13

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