8P1F
X-ray structure of acetylcholine-binding protein (AChBP) in complex with FL001909.
Summary for 8P1F
Entry DOI | 10.2210/pdb8p1f/pdb |
Descriptor | Acetylcholine-binding protein, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-azanyl-1-phenyl-piperidine-4-carboxylic acid, ... (4 entities in total) |
Functional Keywords | fragment based drug design, acetylcholine-binding protein, choline-binding proteins, choline-binding protein |
Biological source | Lymnaea stagnalis (great pond snail) |
Total number of polymer chains | 20 |
Total formula weight | 544742.91 |
Authors | Cederfelt, D.,Boronat, P.,Dobritzsch, D.,Hennig, S.,Fitzgerald, E.A.,de Esch, I.J.P.,Danielson, U.H. (deposition date: 2023-05-12, release date: 2024-05-08, Last modification date: 2024-11-13) |
Primary citation | Fitzgerald, E.A.,Cederfelt, D.,Boronat, P.,Aarmo Lund, B.,de Esch, I.J.P.,Danielson, U.H. Elucidating the regulation of ligand gated ion channels via biophysical studies of ligand-induced conformational dynamics of acetylcholine binding proteins To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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