8OQA
CryoEM structure of human rho1 GABAA receptor in complex with GABA and picrotoxin
Summary for 8OQA
Entry DOI | 10.2210/pdb8oqa/pdb |
EMDB information | 17110 |
Descriptor | Gamma-aminobutyric acid receptor subunit rho-1, 2-acetamido-2-deoxy-beta-D-glucopyranose, HEXANE, ... (7 entities in total) |
Functional Keywords | gabaa receptor, rho1, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 5 |
Total formula weight | 284505.39 |
Authors | Chen, F.,Victor, T.,John, C.,Rebecca, J.H.,Lindahl, E. (deposition date: 2023-04-11, release date: 2023-08-30, Last modification date: 2024-02-07) |
Primary citation | Cowgill, J.,Fan, C.,Haloi, N.,Tobiasson, V.,Zhuang, Y.,Howard, R.J.,Lindahl, E. Structure and dynamics of differential ligand binding in the human rho-type GABA A receptor. Neuron, 111:3450-3464.e5, 2023 Cited by PubMed: 37659407DOI: 10.1016/j.neuron.2023.08.006 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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