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8OQA

CryoEM structure of human rho1 GABAA receptor in complex with GABA and picrotoxin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E
(A, B, C, D, E)
Gamma-aminobutyric acid receptor subunit rho-1polymer47955950.25UniProt (P24046)
Pfam (PF02931)
Pfam (PF02932)
Homo sapiens (human)GABA(A) receptor subunit rho-1,GABA(C) receptor
2AA, F, FA, G, GA...
(C, A, D, E, B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.210Chemie (NAG)
3CA, DA, H, HA, I...
(C, A, D, E, B)
HEXANEnon-polymer86.214Chemie (HEX)
4BA, IA, K, V
(C, D, A, B)
N-OCTANEnon-polymer114.24Chemie (OCT)
5M, N
(A)
CHLORIDE IONnon-polymer35.52Chemie (CL)
6EA, LA, O, P, Y
(D, E, B, C)
GAMMA-AMINO-BUTANOIC ACIDnon-polymer103.15Chemie (ABU)
7X
(B)
(1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dionenon-polymer292.31Chemie (RI5)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight279751.2
Non-Polymers*Number of molecules36
Total formula weight4754.2
All*Total formula weight284505.4
*Water molecules are not included.

246905

PDB entries from 2025-12-31

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