8K3S
Structure of PKD2-F604P complex
Summary for 8K3S
Entry DOI | 10.2210/pdb8k3s/pdb |
EMDB information | 36858 |
Descriptor | Polycystin-2, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | ion channel, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 269581.72 |
Authors | Chen, M.Y.,Su, Q.,Wang, Z.F.,Yu, Y. (deposition date: 2023-07-16, release date: 2024-04-03, Last modification date: 2024-05-22) |
Primary citation | Wang, Z.,Chen, M.,Su, Q.,Morais, T.D.C.,Wang, Y.,Nazginov, E.,Pillai, A.R.,Qian, F.,Shi, Y.,Yu, Y. Molecular and structural basis of the dual regulation of the polycystin-2 ion channel by small-molecule ligands. Proc.Natl.Acad.Sci.USA, 121:e2316230121-e2316230121, 2024 Cited by PubMed: 38483987DOI: 10.1073/pnas.2316230121 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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