8JRL
Crystal structure of P450 TleB with an indole alkaloid
Summary for 8JRL
Entry DOI | 10.2210/pdb8jrl/pdb |
Descriptor | Cytochrome P-450, PROTOPORPHYRIN IX CONTAINING FE, (2~{S})-~{N}-[(2~{S})-1-(4-fluoranyl-1~{H}-indol-3-yl)-3-oxidanyl-propan-2-yl]-3-methyl-2-sulfanyl-butanamide, ... (4 entities in total) |
Functional Keywords | cytochrome p450, heme binding, iron ion binding, oxidoreductase |
Biological source | Streptomyces blastmyceticus |
Total number of polymer chains | 1 |
Total formula weight | 47961.46 |
Authors | |
Primary citation | Ge, X.Y.,Long, Y.,Wang, J.,Gu, B.,Yang, Z.X.,Feng, Y.Y.,Zheng, S.,Li, Y.Y.,Yan, W.P.,Song, H. Regulation of P450 TleB catalytic flow for the synthesis of sulfur-containing indole alkaloids by substrate structure-directed strategy. and protein engineering. Sci China Chem, 66:3232-3241, 2023 Cited by DOI: 10.1007/s11426-023-1755-4PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.07 Å) |
Structure validation
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