8JHL
GDP-bound KRAS G12D in complex with YK-8S
Summary for 8JHL
Entry DOI | 10.2210/pdb8jhl/pdb |
Descriptor | GTPase KRas, N-terminally processed, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | hydrolase/inhibitor, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 20578.16 |
Authors | |
Primary citation | Yu, Z.,He, X.,Wang, R.,Xu, X.,Zhang, Z.,Ding, K.,Zhang, Z.M.,Tan, Y.,Li, Z. Simultaneous Covalent Modification of K-Ras(G12D) and K-Ras(G12C) with Tunable Oxirane Electrophiles. J.Am.Chem.Soc., 145:20403-20411, 2023 Cited by PubMed: 37534597DOI: 10.1021/jacs.3c05899 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.10004053415 Å) |
Structure validation
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