8JBY
Vascular endothelial protein tyrosine phosphatase in complex with Cpd-2
Summary for 8JBY
Entry DOI | 10.2210/pdb8jby/pdb |
Related | 8JBN |
Descriptor | Receptor-type tyrosine-protein phosphatase beta, 4-(hydroxymethyl)-5-(1-methylindol-3-yl)-1,2-oxazole-3-carboxylic acid, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | protein tyrosine phosphatase, fbdd, inhibitor, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 69258.20 |
Authors | |
Primary citation | Asano, W.,Yamanaka, K.,Ohara, Y.,Uhara, T.,Doi, S.,Orita, T.,Iwanaga, T.,Adachi, T.,Fujioka, S.,Akaki, T.,Ikegashira, K.,Hantani, Y. Fragment-Based Discovery of Novel VE-PTP Inhibitors Using Orthogonal Biophysical Techniques. Biochemistry, 62:2161-2169, 2023 Cited by PubMed: 37414577DOI: 10.1021/acs.biochem.3c00079 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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