8JBY
Vascular endothelial protein tyrosine phosphatase in complex with Cpd-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Receptor-type tyrosine-protein phosphatase beta | polymer | 295 | 34056.5 | 2 | UniProt (P23467) Pfam (PF00102) | Homo sapiens (human) | Protein-tyrosine phosphatase beta,R-PTP-beta,Vascular endothelial protein tyrosine phosphatase,VE-PTP |
| 2 | C, G (A, B) | 4-(hydroxymethyl)-5-(1-methylindol-3-yl)-1,2-oxazole-3-carboxylic acid | non-polymer | 272.3 | 2 | Chemie (U7L) | |||
| 3 | D, E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | F, H (A, B) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 298 | Chemie (HOH) |
Sequence modifications
A, B: 1686 - 1971 (UniProt: P23467)
| PDB | External Database | Details |
|---|---|---|
| Gly 1677 | - | expression tag |
| Pro 1678 | - | expression tag |
| Leu 1679 | - | expression tag |
| Gly 1680 | - | expression tag |
| Ser 1681 | - | expression tag |
| Pro 1682 | - | expression tag |
| Gly 1683 | - | expression tag |
| Ile 1684 | - | expression tag |
| Pro 1685 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68112.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1145.3 | |
| All* | Total formula weight | 69258.2 |
