8IMY

Cryo-EM structure of GPI-T (inactive mutant) with GPI and proULBP2, a proprotein substrate

Summary for 8IMY

• Entry DOI: 10.2210/pdb8imy/pdb
• Related: 7W72 7WLD
• EMDB information: 32336 32582 35576
• Descriptor: Glycosylphosphatidylinositol anchor attachment 1 protein,GFP-like fluorescent chromoprotein cFP484, CHOLESTEROL HEMISUCCINATE, MAGNESIUM ION, ... (19 entities in total)
• Functional Keywords: cryo-em, glycosylphosphatidylinositol, gpi, gpi anchored protein, gpi-ap, membrane protein complex, proprotein, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 483228.67

Authors

Li, T.,Xu, Y.,Qu, Q.,Li, D. (deposition date: 2023-03-07, release date: 2023-08-16, Last modification date: 2023-11-01)

• Primary citation: Xu, Y.,Li, T.,Zhou, Z.,Hong, J.,Chao, Y.,Zhu, Z.,Zhang, Y.,Qu, Q.,Li, D.; Structures of liganded glycosylphosphatidylinositol transamidase illuminate GPI-AP biogenesis.; Nat Commun, 14:5520-5520, 2023; PubMed: 37684232; DOI: 10.1038/s41467-023-41281-y

Experimental method

ELECTRON MICROSCOPY (3.22 Å)