8HYC
Crystal structure of B1 NDM-1 MBL in complex with 2-amino-5-(2-(thiophen-2-yl)ethyl)thiazole-4-carboxylic acid
Summary for 8HYC
Entry DOI | 10.2210/pdb8hyc/pdb |
Descriptor | Metallo-beta-lactamase type 2, ZINC ION, 2-azanyl-5-(2-thiophen-2-ylethyl)-1,3-thiazole-4-carboxylic acid, ... (4 entities in total) |
Functional Keywords | beta-lactamase class b ndm-1, hydrolase |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 2 |
Total formula weight | 51919.83 |
Authors | |
Primary citation | Yan, Y.-H.,Zhu, K.-R.,Yang, L.-L.,Li, G.-B. 2-Aminothiazole-4-carboxylic acids as cross-class metallo-beta-lactamase inhibitors by mimicking beta-lactam hydrolysate binding To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.151 Å) |
Structure validation
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