8HGP
The EREG-bound EGFR/HER2 ectodomain complex
Summary for 8HGP
Entry DOI | 10.2210/pdb8hgp/pdb |
EMDB information | 34745 |
Descriptor | Receptor tyrosine-protein kinase erbB-2, Epidermal growth factor receptor, Proepiregulin, ... (6 entities in total) |
Functional Keywords | membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 170418.96 |
Authors | |
Primary citation | Bai, X.,Sun, P.,Wang, X.,Long, C.,Liao, S.,Dang, S.,Zhuang, S.,Du, Y.,Zhang, X.,Li, N.,He, K.,Zhang, Z. Structure and dynamics of the EGFR/HER2 heterodimer. Cell Discov, 9:18-18, 2023 Cited by PubMed: 36781849DOI: 10.1038/s41421-023-00523-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.53 Å) |
Structure validation
Download full validation report