8H7L

Cryo-EM Structure of SARS-CoV-2 BA.2 Spike protein in complex with BA7535

Summary for 8H7L

• Entry DOI: 10.2210/pdb8h7l/pdb
• EMDB information: 34522
• Descriptor: Spike glycoprotein, BA7535 fab heavt chain, BA7535 fab light chain, ... (5 entities in total)
• Functional Keywords: sars-cov-2 ba.2, spike, fab, cryo-em, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV,SARS-CoV-2); More
• Total number of polymer chains: 9
• Total formula weight: 601217.58

Authors

Liu, Z.,Yan, A.,Gao, Y. (deposition date: 2022-10-20, release date: 2023-08-30, Last modification date: 2024-03-13)

• Primary citation: Wang, Y.,Yan, A.,Song, D.,Duan, M.,Dong, C.,Chen, J.,Jiang, Z.,Gao, Y.,Rao, M.,Feng, J.,Zhang, Z.,Qi, R.,Ma, X.,Liu, H.,Yu, B.,Wang, Q.,Zong, M.,Jiao, J.,Xing, P.,Pan, R.,Li, D.,Xiao, J.,Sun, J.,Li, Y.,Zhang, L.,Shen, Z.,Sun, B.,Zhao, Y.,Zhang, L.,Dai, J.,Zhao, J.,Wang, L.,Dou, C.,Liu, Z.,Zhao, J.; Identification of a highly conserved neutralizing epitope within the RBD region of diverse SARS-CoV-2 variants.; Nat Commun, 15:842-842, 2024; PubMed: 38287016; DOI: 10.1038/s41467-024-45050-3

Experimental method

ELECTRON MICROSCOPY (2.44 Å)