8GXG

The crystal structure of SARS-CoV-2 main protease in complex with 14a

Summary for 8GXG

• Entry DOI: 10.2210/pdb8gxg/pdb
• Descriptor: 3C-like proteinase nsp5, N-[(2S)-3-(4-fluorophenyl)-1-oxidanylidene-1-[[(2S,3S)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-1-benzofuran-2-carboxamide (3 entities in total)
• Functional Keywords: sars-cov-2, main protease, 3clpro, mpro, viral protease, 14a, hydrolase
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
• Total number of polymer chains: 1
• Total formula weight: 34440.21

Authors

Zhao, Y.,Zhao, J.,Shao, M.,Yang, H.,Rao, Z. (deposition date: 2022-09-20, release date: 2023-09-27)

• Primary citation: Zhao, Y.,Zhao, J.,Shao, M.,Yang, H.,Rao, Z.; The crystal structure of SARS-CoV-2 main protease in complex with 14a; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.69 Å)