8GAT
Structure of human NDS.1 Fab and 1G01 Fab in complex with influenza virus neuraminidase from A/Indiana/10/2011 (H3N2v), based on consensus cryo-EM map with only Fab 1G01 resolved
Summary for 8GAT
Entry DOI | 10.2210/pdb8gat/pdb |
EMDB information | 29907 29908 29909 |
Descriptor | Vasodilator-stimulated phosphoprotein, Neuraminidase chimera, Fab 1G01, heavy chain, Fab 1G01, light chain, ... (4 entities in total) |
Functional Keywords | neuraminidase, antibody, influenza, viral protein-immune system complex, viral protein/immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 102342.24 |
Authors | Tsybovsky, Y.,Lederhofer, J.,Kwong, P.D.,Kanekiyo, M. (deposition date: 2023-02-23, release date: 2024-02-28, Last modification date: 2024-04-24) |
Primary citation | Lederhofer, J.,Tsybovsky, Y.,Nguyen, L.,Raab, J.E.,Creanga, A.,Stephens, T.,Gillespie, R.A.,Syeda, H.Z.,Fisher, B.E.,Skertic, M.,Yap, C.,Schaub, A.J.,Rawi, R.,Kwong, P.D.,Graham, B.S.,McDermott, A.B.,Andrews, S.F.,King, N.P.,Kanekiyo, M. Protective human monoclonal antibodies target conserved sites of vulnerability on the underside of influenza virus neuraminidase. Immunity, 57:574-586.e7, 2024 Cited by PubMed: 38430907DOI: 10.1016/j.immuni.2024.02.003 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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