8G8C
Crystal structure of DH1322.1 Fab in complex with HIV proximal MPER peptide
Summary for 8G8C
Entry DOI | 10.2210/pdb8g8c/pdb |
Related | 8G8A 8G8D |
Descriptor | DH1322.1 heavy chain, DH1322.1 light chain, Env polyprotein, ... (6 entities in total) |
Functional Keywords | hiv, neutralizing antibody, mper, gp41, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 6 |
Total formula weight | 103304.89 |
Authors | Niyongabo, A.,Janus, B.M.,Ofek, G. (deposition date: 2023-02-17, release date: 2024-05-22, Last modification date: 2024-06-19) |
Primary citation | Williams, W.B.,Alam, S.M.,Ofek, G.,Erdmann, N.,Montefiori, D.C.,Seaman, M.S.,Wagh, K.,Korber, B.,Edwards, R.J.,Mansouri, K.,Eaton, A.,Cain, D.W.,Martin, M.,Hwang, J.,Arus-Altuz, A.,Lu, X.,Cai, F.,Jamieson, N.,Parks, R.,Barr, M.,Foulger, A.,Anasti, K.,Patel, P.,Sammour, S.,Parsons, R.J.,Huang, X.,Lindenberger, J.,Fetics, S.,Janowska, K.,Niyongabo, A.,Janus, B.M.,Astavans, A.,Fox, C.B.,Mohanty, I.,Evangelous, T.,Chen, Y.,Berry, M.,Kirshner, H.,Van Itallie, E.,Saunders, K.O.,Wiehe, K.,Cohen, K.W.,McElrath, M.J.,Corey, L.,Acharya, P.,Walsh, S.R.,Baden, L.R.,Haynes, B.F. Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans. Cell, 187:2919-2934.e20, 2024 Cited by PubMed: 38761800DOI: 10.1016/j.cell.2024.04.033 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.08 Å) |
Structure validation
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