8FKC

Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and inverse agonist SR33544

Summary for 8FKC

• Entry DOI: 10.2210/pdb8fkc/pdb
• Descriptor: Peroxisome proliferator-activated receptor gamma, Nuclear receptor corepressor 1, 2-chloro-N-(5-cyanopyridin-3-yl)-5-nitrobenzamide, ... (5 entities in total)
• Functional Keywords: nuclear receptors, tzds, drug design, therapeutic targets, transcription, transcription-agonist complex
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 34380.14

Authors

MacTavish, B.S.,Kojetin, D.J. (deposition date: 2022-12-21, release date: 2024-04-17)

• Primary citation: MacTavish, B.S.,Kojetin, D.J.; Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and SR33544; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.42 Å)