8FKC
Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and inverse agonist SR33544
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Peroxisome proliferator-activated receptor gamma | polymer | 276 | 31506.6 | 1 | UniProt (P37231) Pfam (PF00104) In PDB | Homo sapiens (human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
| 2 | D | Nuclear receptor corepressor 1 | polymer | 23 | 2508.8 | 1 | UniProt (O75376) In PDB | Homo sapiens (human) | N-CoR,N-CoR1 |
| 3 | A | 2-chloro-N-(5-cyanopyridin-3-yl)-5-nitrobenzamide | non-polymer | 302.7 | 1 | Chemie (Y5F) | |||
| 4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | water | water | 18.0 | 269 | Chemie (HOH) |
Sequence modifications
A: 203 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Gly 202 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34015.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 364.7 | |
| All* | Total formula weight | 34380.1 |
