8F5B

Human ABCA4 structure in complex with AMP-PNP

Summary for 8F5B

Entry DOI	10.2210/pdb8f5b/pdb
EMDB information	28864
Descriptor	Retinal-specific phospholipid-transporting ATPase ABCA4, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	abc transporter, importer, membrane protein, transport protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	258657.82
Authors	Scortecci, J.F.,Van Petegem, F.,Molday, R.S. (deposition date: 2022-11-13, release date: 2023-11-22, Last modification date: 2024-09-18)
Primary citation	Scortecci, J.F.,Garces, F.A.,Mahto, J.K.,Molday, L.L.,Van Petegem, F.,Molday, R.S. Structural and functional characterization of the nucleotide-binding domains of ABCA4 and their role in Stargardt disease. J.Biol.Chem., 300:107666-107666, 2024 Cited by PubMed: 39128720 DOI: 10.1016/j.jbc.2024.107666 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.95 Å)

Structure validation