8EUQ

Crystal structure of HLA-DRA*01:01/HLA-DRB1*04:01 in complex with c44H10 Fab

Summary for 8EUQ

• Entry DOI: 10.2210/pdb8euq/pdb
• Descriptor: HLA class II histocompatibility antigen, DR alpha chain, c44H10 Fab light chain, Hemagglutinin HA1 chain,HLA class II histocompatibility antigen DR beta chain, ... (7 entities in total)
• Functional Keywords: mhc class ii, hla-dr, antibody, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 192812.35

Authors

Kassardjian, A.,Julien, J.-P. (deposition date: 2022-10-19, release date: 2023-04-19, Last modification date: 2023-10-25)

• Primary citation: Kassardjian, A.,Sun, E.,Sookhoo, J.,Muthuraman, K.,Boligan, K.F.,Kucharska, I.,Rujas, E.,Jetha, A.,Branch, D.R.,Babiuk, S.,Barber, B.,Julien, J.P.; Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses.; Cell Rep, 42:112391-112391, 2023; PubMed: 37053069; DOI: 10.1016/j.celrep.2023.112391

Experimental method

X-RAY DIFFRACTION (3.09 Å)