8E47

E. coli 50S ribosome bound to antibiotic analog SLC26

This is a non-PDB format compatible entry.

Summary for 8E47

• Entry DOI: 10.2210/pdb8e47/pdb
• EMDB information: 27882
• Descriptor: 23S ribosomal RNA, 50S ribosomal protein L34, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-({3,4,6-trideoxy-3-[(2-{[2-({[(5S)-3-{(4M)-3-fluoro-4-[(6P)-6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl}amino)-2-oxoethyl]sulfanyl}ethyl)(methyl)amino]-beta-D-xylo-hexopyranosyl}oxy)-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside, ... (11 entities in total)
• Functional Keywords: antibiotics, ribosome
• Biological source: Escherichia coli; More
• Total number of polymer chains: 10
• Total formula weight: 1110282.27

Authors

Pellegrino, J.,Lee, D.J.,Fraser, J.S.,Seiple, I.B. (deposition date: 2022-08-17, release date: 2023-06-28, Last modification date: 2024-06-12)

• Primary citation: Yeon, S.K.,Pellegrino, J.,Lee, D.J.,Seiple, I.B.,Fraser, J.S.; SLC collection of antibiotic analogs; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.32 Å)