8D4U
Crystal Structure of Neutrophil Elastase Inhibited by Eap2 from S. aureus
Summary for 8D4U
Entry DOI | 10.2210/pdb8d4u/pdb |
Related | 8D4Q 8D4S |
Descriptor | Neutrophil elastase, Extracellular Adherence Protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | protease inhibitor, immune evasion, neutrophil, s. aureus, protein binding, hydrolase-inhibitor, protein binding complex, hydrolase/inhibitor |
Biological source | Staphylococcus aureus subsp. aureus More |
Total number of polymer chains | 4 |
Total formula weight | 70047.09 |
Authors | Gido, C.D.,Herdendorf, T.J.,Geisbrecht, B.V. (deposition date: 2022-06-02, release date: 2022-12-21, Last modification date: 2023-10-25) |
Primary citation | Gido, C.D.,Herdendorf, T.J.,Geisbrecht, B.V. Characterization of two distinct neutrophil serine protease-binding modes within a Staphylococcus aureus innate immune evasion protein family. J.Biol.Chem., 299:102969-102969, 2023 Cited by PubMed: 36736422DOI: 10.1016/j.jbc.2023.102969 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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